Orig3n Review

UPDATED Jun. 2024
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Orig3n is a successful startup company founded in 2014 in Boston, Massachusetts. It specializes in biotechnology, specifically in developing cutting-edge treatments for rare genetic conditions targeting liver, heart, and neurodegenerative indications.

Its work may usher an era without trial and error in disease treatment. Ideally, this will enable us to lead healthier and longer lives. Orig3n’s pioneering breakthroughs in regenerative medicine aim at creating an induced pluripotent stem cell technology, which will be able to “shapeshift” into any type of cell in our bodies.

Several A-series investors have realized the importance of its scientific work and backed it with more than 15 million dollars in donations. Our Orig3n review will inspect its complete offer in detail and relay the most important information to you in a succinct and comprehensive fashion.

Orig3n Review homepage

How Orig3n Works

Orig3n follows the direct-to-customer model, with at-home, easy-to-use testing kits. The procedure includes the following steps:

  • Placing an online order You can simply pick the DNA test that caught your interest and order it through the Orig3n website.
  • Sample collection The test uses buccal cells for your DNA analysis, so you’ll be required to perform a cheek swab. It’s a completely painless procedure that only takes up several minutes of your time.
  • Mailing the specimen back Once your cheek swabs are ready, you can mail the kit back to Orig3n for processing, using the pre-paid mailer.
  • Downloading the app LifeProfile app is required for viewing your results. Through this app, you’ll also be able to stay up-to-date with the newest products Orig3n has to offer.

Alternatively, you can also attend one of the many events organized by Orig3n, so you can provide your DNA sample there, without ordering the testing kit.

Why Choose Orig3n

A widely spread saying states that Orig3n is today what the Internet was in 1993. It offers so much more than simple DNA testing and enumerating reasons for looking its way could take quite a while.

We’ll focus on the most important benefits this company provides, including:

  • Variety of detailed and pragmatic DNA tests
  • Revolutionary scientific approach based on Nobel Prize winning technology
  • State-of-the-art processing facility
  • Compliance with protocols established by Occupational Safety & Health Administration and The World Health Organization
  • Highly trained and professional staff
  • Reasonable pricing
  • Family discounts
  • Constant activity on pushing the boundaries in the field of regenerative medicine for the common good
  • Opportunity for customers to contribute to ongoing research projects exploring the usage of iPS cells for testing drugs for efficacy and ways to personalize the treatment approach


Orig3n currently offers 20 DNA tests, each providing a crucial insight into your personal fitness potential, response to nutrients, overall wellness, and genetic predispositions.

Individuals under 18 years of age must provide parental/guardian consent in order to participate. There’s no upper age limit, as long as there are no limitations or restrictions preventing you from providing a viable sample.

Particular genes selected for testing are recommended by leading research and peer-reviewed scientific publications. The average turnaround across the tests is around 4 weeks after the receipt of your DNA sample. Orig3n strongly encourages involving your family members in DNA testing, so it offers family discounts on all tests.

Fitness (149$)

This test assesses and decodes information stored in your DNA signature, providing a full insight into your fitness potential.

The test covers:

  • Power performance – Testing genetic variants associated with cardiovascular fitness and the makeup of skeletal muscles located in fast-twitch muscle fibers.
  • Exercise recovery – Determining the time frame needed for you to recover from a high-intensity exercise.
  • Metabolism – Identifying fat mass and genetic level of fat sensitivity, alongside cholesterol regulation degree, insulin sensitivity, and lipid metabolism.
  • Muscle strength  Establishing the true potential of your muscle power based on genes in charge of bone density, immune function, and muscle mass.
  • Endurance Providing information on the overall effectiveness of your body’s ability to process oxygen. Genes tested are responsible for red blood cell production, inflammation management, muscle efficiency, and tissue oxygenation.
  • Joints Analyzing genetic variations in the makeup of your ligaments, tendons, and cartilage. These differences affect how sore you will get after working out.

You can also order different subsets of this test, including:

  • Metabolism DNA Test (49.00$)
  • Joint Care DNA Test (39.00$)
  • Recovery & Renewal DNA Test (39.00$)
Orig3n fitcode test
Orig3n fitcode

Beauty (99$)

Beauty  is a skin assessment test providing unprecedented information about your largest organ. Orig3n tests 8 separate genes and their related single nucleotide polymorphisms.

The test covers:

  • Skin hydration capacity Understanding your skin’s genetic hydration qualities can help you tailor your water consumption and skin care accordingly.
  • Aging Genetic capacity for skin aging varies among people, so being familiar with yours is essential for proper skin care. If the test determines that you have genetic predispositions for faster-than-normal aging, you’ll be able to take extra steps in advance to better preserve and protect your skin.
  • Elasticity Elasticity is one of the most important features to maintain if you want your skin to age well. A proper understanding of your genetic markers can basically provide a roadmap, outlining the best ways of doing so.
  • UV sensitivity This portion of the test will inform you whether your sensitivity to the sun is higher-than-normal, so you can protect your skin adequately.

This testing branch allows for the following subsets:

  • Skin Health & Appearance (49.00$)
  • Hair DNA Test (39.00$)
  • Skin Aging DNA Test (49.00$)
Orig3n fitcode test
Orig3n aura test

Nutrition (149$)

This test identifies your body’s natural response to nutrition. The results can help you customize your diet plan the way you were genetically predisposed to do.

The test covers:

  • Food sensitivity Indicating food limitations you should introduce to your daily diet, the most prominent factors including milk, caffeine, and alcohol.
  • Food breakdown Teaching you about your body’s ability to metabolize good and bad fats present in your diet. This section focuses on lipid levels, HDL/LDL cholesterol, fatty acid response, and monounsaturated fat.
  • Hunger and weight Focusing on your genetic predispositions concerning appetite, metabolic rate, key determinants of weight loss/gain, and sugar cravings.
  • Vitamins Genetics can make the production of certain vitamins harder for your body, so you’ll learn about your potential vitamin deficiencies and needed supplements.

You can order the following subsets individually:

  • Caffeine Tolerance DNA Test (29.00$)
  • Lactose Intolerance DNA Test (29.00$)
  • Hunger & Weight DNA Test (49.00$)
  • Folate DNA Test (29.00$)
  • Alcohol Tolerance DNA Test (29.00$)
  • Vitamins (49.00$)
Orig3n fuel test
Orig3n fuel

Superhero (29$)

This test should help you determine your “superpower.”

The test covers:

  • Strength If you belong to the 10% of people with an inherent genetic strength attribute, you’ll possess the highest muscle strength, thus the lowest risk percentage for muscle injury.
  • Intelligence Determines your genetic ability to digest information quickly, presenting DNA predisposition for higher academic achievements.
  • Speed Explores your DNA for a particular muscle protein, enabling your skeletal muscles to generate force at high momentum.
Orig3n superhero
Orig3n superhero test

Behavior (79$)

The test should uncover the secrets of your brain, as stated by Orig3n, providing a complete picture of your personal behaviorism.

The test covers:

  • Addiction Determining your genetic predispositions for handling the effects of cannabis, alcohol, and other opiates.
  • Feelings Teaching you about your genetic mold for euphoria, empathy, and stimulation.
  • Behavior Establishing how your DNA affects your motor skills and impulsive behavior.
  • Tolerance – Examining your tolerance levels for pain and stress.

You can share the results with your doctor, providing him/her with an unprecedented insight into your genetic makeup.

Orig3n bliss test
Orig3n bliss

Child Development (99$)

This test decodes your child’s DNA, providing information on unique genetic traits and properties.

The results focus on the following key aspects of your child’s development:

  • Enlightenment – This segment tests genes related to cognitive abilities, memory recall, and mathematical skills.
  • Fitness – The genes inspected affect sports performance in terms of endurance, muscle force, strength, and other capabilities.
  • Health Explores the role of your child’s DNA regarding overall health, from sleep issues to potential tooth decay.
  • Nutrition Helps you build a customized diet plan to fit your child’s genetic needs.

You can also share the findings with your pediatrician in order to provide him/her with information about your child’s unique genetic composition.

Orig3n bloom
Orig3n bloom test

John Lynch Gameplan (79.00$)

This is a gene profiling test that measures your raw potential for football.

The test covers:

  • Performance – Checking your genes related to athletic performance.
  • Toughness – Examining your genetic capacity for musculoskeletal strength.
  • Resilience – Determining your genetic capacity to “bounce back” after taking a hit.
  • Spirit – Exploring your ability to stay positive and connected with your team.

ALDH2 Deficiency (29.00$)

This test will detect your body’s ability to break down acetaldehyde (a byproduct of alcohol), which is also found in tea, coffee, and air pollution.

The test covers:

  • ALDH2 (alcohol tolerance)
  • BCMO1 (beta-carotene, vitamin C)
  • SLC23A1 (Vitamin C)


Orig3n runs the largest crowdsourced biorepository of induced pluripotent stem cells in the world, simply named the LifeCapsule. The collection of donated blood samples enables scientists to create iPS cells and perform numerous tests in order to better understand cryptic and rare diseases.

You can also take part in the advancement of your future health and medicine in general by joining the LifeCapsule program. The price of the annual membership is 99$, enabling you to:

  • Add your DNA sample to the repository
  • Learn all about the usage of your sample in developing new potential treatments
  • Get exclusive access to future services the moment they’re online
  • Have everlasting access to your personal and immortalized iPS cells

Orig3n also offers C3LL Cardiomyocytes derived from human-induced pluripotent cells. They display the typical morphology with Troponin T expression and synchronous beating as markers for differentiated cardiomyocytes.

Privacy And Security

Orig3n takes your privacy seriously, so you can rest assured that it will never share your contact/payment information or test results with any third parties. Only you have access to your results through the designated app and only you know who the DNA sample belongs to.

Shipping And Handling

Orig3n doesn’t mention anything about shipping options, so we presume it uses regular postal service, which enables you to choose between regular and express shipping. It also doesn’t state its region coverage, so we don’t actually know whether it ships its DNA testing kits worldwide or just within the US.

Bottom Line

Our Orig3n review painted a picture of a revolutionary company pushing the boundaries in the field of regenerative medicine. Apart from providing a variety of high-quality DNA tests, it works on equipping doctors with new tools for handling rare genetic diseases. Orig3n also enables its customers to participate in its research and immortalize their blood sample in the form of iPS cells.

It is the only company of this kind on the market and its business model and dedication have already attracted numerous high-rolling investors and thousands upon thousands of customers.

User Reviews (20)

Orig3n customer rating based on 20 user reviews.

The Orig3n reviews listed below reflect the opinions and experiences of real users and are in no way influenced by the company reviewed here. Before publishing each review, our team checks whether it was submitted by an actual user in an effort to prevent false or spammy reviews.

  1. Melissa | December 23, 2020

    Make sure you do a little research before you use this company. You will find that the majority of people who send in a DNA sample do not receive their results and get not contact from the company. Sent in a sample in March and have received nothing as of today.

  2. Simone | November 28, 2020

    Same happened to me. Received a confirmation in May 2020. It is now end of November – 6 months later and no results or communication whatsoever. Also bought through noom. I have sent 2 emails and made a phone call. Absolutely no response. Trying to see now if noom can get me a refund or a response. I have asked them before and they said couldn’t do anything because of privacy. If I don’t get anywhere I will contact my credit card company and file a claim since I never received the service. Really is zero stars. Gave one star because zero is not in the list!

  3. ANALISA GONZALEZ | October 7, 2020

    A scam that’s what it is! Got it through Noom. What a waste of money. Never got my results!

  4. Susan Tousley | September 30, 2020

    Wow! I have had the same experience as many, many people. I wish I had never purchased it since there has been nothing but frustration! This is my second go around with a test since way back. They claimed that the sample wasn’t good. So here I wait for the second test Results that I sent in months ago.
    Don’t waste your time and money on this!

  5. Lucy | September 22, 2020

    Received confirmation on June 30, 2020 Orig3n received and “we’re analyzing segments of” and “we’re almost there” with my results. There has been no other communication since then. Twelve weeks today since I submitted my DNA kit and almost 12 weeks since they told me they were almost finished with the testing. I submitted a ticket and was told someone would contact me within 72 hours; 12 days later and no one has contacted me. As of today, still no results or returned emails. I finally received a phone call from a message I left earlier and was told that 7 of the 16 lab results had been published; however, there was not enough information to provide me a partial report, AND, they could not tell me how much longer it would take to complete the results of the remainder of the tests. EXTREMELY FRUSTATED!

  6. Nancy | August 20, 2020

    I sent my first sample in March. In June I still did not have results. Customer service did not respond until I involved Noom as I had purchased the service through them. I was asked to send it two more samples. They were received on June 14 and I was told they would be done in a few weeks. In August I received partial results. It has now been over 8 weeks and I do not have complete results. I have complained to the BBB. The company offered to refund my money, even though they do not usually do that when partial results have been given. I have asked if they can tell me when my results can be expected, but I have not received a response. I would not recommend this company. There customer service is slow to respond and they do not give results in a timely manner. It has been almost 6 months and three samples later and I still do not have complete results.

  7. Emily R Lalonde | July 29, 2020

    Very disappointed to see several reviews are similar to my situation. I received a confirmation email on May 14, 2020 that my DNA was received and it would be 6-8 weeks for results. Today is July 29, 2020 and I still have no results.

    I have emailed several times trying to get a status and I have not heard back from one person.

    I would really appreciate if someone from the company would respond and let me know what is going on.

  8. Jill Yanus | July 14, 2020

    Do not purchase Orig3n unless you want to waste your money. 6-8 weeks is not true for results. I have been waiting 12 weeks with no response from the company with support tickets submitted.

  9. kal100 | July 6, 2020

    Sent payment thru NOOM and swabs into ORIG3N in March. Only got a partial report.
    Sent numerous emails over the last few months about receiving an incomplete report.
    It IS NOT a 4-6 week turnaround.
    If they can’t meet their own turnaround time, the website should be updated or they should communicate better with customers.

  10. Patricia Saenz | June 18, 2020

    Horrible experience,
    Ordered through NOOM (another huge disappointment).
    Mailed in sample at the end of a January 2020.

    Today is June 18, 2020!

    First sample was lost for a month! No explanation.

    Late April I was informed that my sample was not enough to perform complete test.

    I mailed back the second sample , they confirmed receipt on May 11th.

    Was informed that the delay was due to overload of COVID-19 testing..

    At this point, I can’t trust them. Don’t believe the report will be worth a penny. I

    I wonder what kind of “lab” they have! Who many people are employed ?
    Poor management!
    NOT customer friendly!
    Automated email responses!

    Zero stars !!!!!!

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