Ranking Criteria Explained
The most important criterion in ranking health DNA tests is the number of genetic diseases and conditions covered. The more illnesses the test checks for, the more accurate the results. In order to verify the accuracy and quality of the tests, we use additional criteria such as the likelihood of test errors and failures, the quality of the processing facilities, and the competency of the staff. Other factors we focus on during our ranking process include overall service quality, average turnaround times, membership benefits, and overall expenses, which are all reliable indicators of potential customer satisfaction.
These are our most important ranking factors, but there’s a number of internal low-impact criteria that help us differentiate between services of a similar quality. Taking into account these factors, we developed our list of the best health DNA tests on the market. You can read their mini-reviews below and prepare to unlock all the health-related secrets hidden in your DNA code.
Our Top Picks
When looking for the best DNA tests to fit your budget, your personal goals, and the overall scope of your genetic exploration, researching all the available options is of paramount importance. Whether you are just interested in satisfying your curiosity or embarking on a serious DNA-related quest, the following mini-reviews will familiarize you with the top at-home testing solutions currently on the market.
MyHeritage is an Israeli at-home DNA testing company founded back in 2003 in Bnei Atarot. From its launch, this provider managed to amass more than 100 million users worldwide and generate over 3.7 billion family tree profiles. Its genealogical database currently features more than 10 billion historical records.
MyHeritage recently introduced its proprietary health-related screening service, which can only be purchased with its well-known ancestry test for 199$ per kit (the stand-alone ancestry test costs 79$). After filling out a health questionnaire, securing your cheek swab in a vial you get with the kit, and sending your kit back to the processing lab, your personal health + ancestry report will be generated within 3-4 weeks.
When it comes to your final results, you will receive 18 genetic risk reports, including polygenic risk estimates for conditions such as breast cancer, type 2 diabetes, and heart disease. Your results will also provide you with 18 carrier status reports, including Gaucher disease, cystic fibrosis, and Tay-Sachs.
The ancestry portion of the results will contain your ethnicity estimates, covering 42 regions (or ethnic populations). You will also gain access to a feature called DNA Matches, which allows you to discover potential genetic relatives within the company’s database, establish the exact relationship path, and contact them if you so choose. You will be able to generate a personal family tree or import your GEDCOM file as well.
Lastly, if you already tested with another provider, MyHeritage lets you upload your raw DNA data and receive your DNA matches absolutely free of charge. On the other hand, advanced DNA features like ethnicity estimates, chromosome browser, and shared ancestral places cost an extra fee.
Ancestry.com LLC is the largest genetic and genealogical conglomerate on the market founded way back in 1983 in Lehi, Utah. Apart from its famous AncestryDNA test, the company incorporates a wide variety of online services, including Archives.com, AncestryHealth, Find a Grave, AncestryProGenealogists, Rootsweb, Family Tree Maker, Newspapers.com, and Fold3.
Recently, Ancestry introduced its proprietary health service called AncestryHealth Core (149$), which allows you to determine how your genetics affects your health and wellness. It is a physician-ordered DNA test utilizing the same microarray technology used in DNA matching and ethnicity-related products. The advanced version called AncestryHealth Plus that will cover a much larger number of genetic variants is still in the works, but you can join the waitlist on the official website.
After collecting your saliva sample and mailing it back to the processing lab, you can expect your final results in about 8 weeks. Your personal information will include health and wellness reports for hereditary breast and ovarian cancer syndrome, Lynch syndrome, cystic fibrosis, sickle cell anemia, Tay-Sachs, and 4 hereditary heart conditions.
Apart from this, Ancestry provides professional counseling and educational materials through its partnership with PWNHealth. You will also gain access to your personal Family health history tool that shows a clear picture of hereditary conditions running in your family, which you can share with your health provider.
Lastly, AncestryHealth Core will also include parts of the AncestryDNA test that will allow you to discover your ethnic origins across more than 1,000 regions of the world.
AncestryHealth Core is a one-time purchase test while AncestryHealth Plus will require a yearly membership for constant updates once it is released.
23andMe is probably the most famous DNA testing provider on the market. It focuses on ancestry genetic exploration but also offers a health-related portion of the results for an extra fee. This makes it the only ancestry service to pay attention to your genetic health.
Launched in 2006, 23andMe is a privately held biotechnology and personal genomics company, with corporate headquarters in Mountain View, California. Its direct-to-customer business model was declared Invention of 2014 by The Times Magazine.
The company’s basic ancestry DNA test, which costs 99$, is a prerequisite for ordering its health test. This, however, might pose a problem to individuals interested only in their genetic health and not ancestral lines. The health test costs an additional 100$.
Your 23andMe health report will check for 10+ genetic health risks (including Late-Onset Alzheimer’s Disease, Hereditary Thrombophilia, Parkinson’s Disease…), 40+ carrier status reports (including Sickle Cell Anemia, Cystic Fibrosis, Hereditary Hearing Loss…), 7+ wellness reports (including Deep Sleep, Genetic Weight, Lactose Intolerance…), and 30+ traits reports (including Sweet vs. Salty, Male Bald Spot, Unibrow…).
The company guarantees anonymous genotyping, allowing customers to use a pseudonym up until they register their personal account. However, your genetic material will be stored separately from your personal data, so no one will be able to connect the two. In other words, the staff connects your DNA sample and results with your unique registration code rather than your name and other personal info.
Orig3n began as a successful startup launched in 2014 in Boston, Massachusetts. The company excels in the field of biotechnology, developing state-of-the-art treatments for genetic conditions affecting heart, liver, and neurodegenerative indications.
The basic skeleton of the company’s business model is based on Nobel Prize-winning technology. It is intended to remove trial & error from the disease treatment process. This will, ideally, bring us a much longer and healthier life. The company’s ultimate effort is focused on creating an induced pluripotent stem cell technology able to create cells that can turn into any type of cell in the human body. This would revolutionize regenerative medicine as we know it.
Orig3n currently offers 20 DNA tests designed to give you an essential insight into your overall wellness, fitness potential, and genetic predispositions. The tests use buccal swabs for DNA sample collection, so the procedure takes only a couple of minutes. Note that individuals under 18 must provide consent form a parent or guardian in order to take any of the tests. There’s no upper age limit as long as you can provide a viable sample. The average turnaround time is around 4 weeks. Orig3n encourages users to include their families in DNA testing in order to provide the most accurate genetic picture possible.
The price tags range from 29$ to 298$. Orig3n also runs the biggest crowdsourced biorepository of induced pluripotent stem cells in the world. The project is called “LifeCapsule” and it allows scientists to experiment and create iPS cells. The annual membership for the LifeCapsule Program is 99$.
Helix is a well-known biotechnology company founded in 2015 in San Mateo, California behind the idea of integrating genomic data into regular clinical care and widening the impact of genetic information with its expertise in bioinformatics and DNA sequencing. All tests are performed in its proprietary CAP-accredited and CLIA-certified next-generation sequencing lab.
Apart from a variety of ancestry and trait tests, Helix provides its users with 5 health-related DNA testing solutions:
GenePrism: Actionable Insights (299.99$) – The test screens 59 genes for variations associated with certain hereditary conditions. The reports are delivered within 4-8 weeks in an easy-to-understand format and you can access in-house counselors at any given moment.
Mayo Clinic GeneGuide (199.99$) – The test covers 4 carrier reports, 4 disease risks, 3 health traits, and your metabolic response to 4 medications. You will also receive comprehensive educational materials and 4 convenient health tools.
Prostate Cancer Genetic Risk Score (239.99) – This test is primarily designed for males of East Asian, African American, and Non-Hispanic white ethnic background. Apart from your GRS for prostate cancer, you will also receive numerous educational materials as well as professional guidance counseling. The final report is generated within 6-10 weeks.
Carrier Check (249.99$) – The test screens for 67 genetic conditions across 65 genes. It is designed for people of all ethnicities and comes with professional genetic counseling after you receive your results.
Alzheimer’s ApoE (194.99$) – By identifying the combination of your ApoE alleles, the test will determine your genetic risk for developing late-onset Alzheimer’s based on your current age and ApoE genotype.
In order to perform any of the aforementioned health DNA tests, you will have to be sequenced by Helix. If you are already a Helix user, the prices of certain testing solutions will be considerably lower.
Since 2014, Vitagene has helped thousands of users make fully informed life choices by unlocking the secrets hidden in their DNA. The company can tell you everything about your past through its ancestry DNA testing but also help you create a healthier future for yourself and your loved ones.
Vitagene combines cutting-edge technology and scientific breakthroughs with convenient and budget-friendly testing options. Its service is equally dedicated to helping people on an individual level and reshaping the healthcare industry as we know it.
Vitagene offers direct-to-customer testing solutions, which means you’ll be able to collect the relevant DNA samples (buccal cells) in the privacy of your own home. You can then simply mail them back to the company’s CLIA and CAP-accredited lab for further processing. Your results will be available 4-6 weeks after the lab receives your samples. You’ll receive an email notification when your report is generated and you’ll be able to inspect it on your personal Vitagene dashboard.
Vitagene currently offers 5 different products: Health Report + Ancestry (79.00$), Health Report (49.00$), Smart Supplements (Essential – 49.00$ per month; Premium – 79.00$ per month), Wellness Bundle (Health Report + Ancestry + 1 month of Essential Supplements – 149.00$), and Vitality Bundle (Wellness Bundle with a 4-month subscription to 4 personalized supplements – 245.00$).
The company only accepts orders made in the US at the moment and sends its DNA testing kit with a prepaid mailer. In other words, you won’t have to worry about the return shipping costs. If you have any doubts or questions, you can contact its user support via email, phone or live chat Mon-Fri 9:00 AM – 6:00 PM PT.
Pathway Genomics is a privately held medical diagnostics company dedicated to providing physicians and their patients with full control of their health and wellness. The company was founded in 2008, with corporate headquarters in San Diego, California.
Jim Plante, the founder of Pathway Genomics, launched the company after his father passed away from an inherited polycystic kidney disease. He was guided by the vision of making budget-friendly personalized medicine and genetic testing accessible to everyone. In 2014, the company partnered with IBM Watson Group OME, resulting in a mobile app based on deep learning and AI.
Pathway Genomics currently offers 10 different DNA tests, 7 designed for home use and 3 that can be ordered by your physician. The at-home tests focus on your physical traits and needs, dietary recommendations, metabolic health factors, and skin care. The prices range from 99$ to 399$. The tests use buccal swabs for DNA sample collection. The average turnaround time is between 2 and 3 weeks.
Physician-only tests also begin with at-home sample collection, but they use saliva or blood. They are divided into 2 categories: Health & Wellness and Carrier Screening (checking for more than 120 recessive genetic disease and conditions).
Pathway Genomics takes good care of your personal information. Note that there are some cases when the company can disclose your info without your consent (payment, treatment purposes, business associates, health care operations, research, family, friends, and caregivers…).
New Life Genetics
New Life Genetics is a DNA testing provider dedicated to uncovering the potential locked in our genetic code and solving major medical mysteries. In order to achieve this, it has gathered an interdisciplinary team of scientists, with staff members specializing in genetics, nutrigenetics, nutrigenomics, fitness, health, nutrition, dietetics, and human nutrition. This cooperation between biotechnology, genetics, and dietetics is everything New Life Genetics stands for.
New Life Genetics features 8 different health DNA tests, all designed to answer some of the most important questions regarding your overall health and wellness. Its testing solutions incorporate everything from weight loss and fitness tests to those designed to combat your stress or problems with skin and acne. The prices range from 118.05 EUR up to 299 EUR, which might seem a bit steep but is definitely justified by the value provided.
New Life Genetics also pays great attention to the safety of user information. It incorporates numerous physical and technical measures in order to ensure the complete security of your sensitive data. All connections to its website are encrypted with SSL technology, so you don’t have to fear your personal or payment details will ever leak to any third party. Your DNA samples are destroyed the moment your final report is generated, but you can also request for them to be permanently stored in the company’s database in case you plan on performing more tests in the future.
TeloYears is a very simple health DNA test developed by Telomere Diagnostics Inc. The company itself was launched back in 2010, with one of the founding members being Dr. Elizabeth Blackburn, the winner of the 2009 Nobel Prize in Medicine for her pioneering work in the field of telomere biology.
The price of TeloYears DNA test is 89 $ and the company also offers the possibility of purchasing its “Now and Later” pack, allowing you to save 31 $. The pack contains two tests that are used to establish the cellular age encoded in your DNA and monitor its progress over the a period of 6 or 12 months. For optimal results, you should repeat the test every year in order to monitor the shortening of your telomeres and the progress of your genetic age.
Note that TeloYears test doesn’t use saliva or buccal swabs but blood as your DNA sample. It analyses the DNA found in your leukocytes by using the company’s proprietary “Cawthon qPCR assay” method. The end result is a very accurate representation of your genetic age with a variability coefficient between 2-3 percent. The results are usually generated in 3-4 weeks.
The final report also includes its free “Blueprint for Aging Well,” which provides a tool for self-assessment, a detailed overview of how certain factors like stress or inflammation affect your health and genetic age, a suggested action plan, and a comprehensive view of the science applied to your case.
Futura Genetics is a company dedicated to healthcare and lifestyle DNA testing. Its goal is to provide the general public with knowledge of the human genome at budget-friendly prices. The company was launched in 2014, with headquarters in Vancouver.
Futura Genetics capitalizes on the fact that recent scientific breakthroughs in DNA sequencing greatly reduced the overall price of genetic extraction, making it available to ordinary users and not just
to big corporations or wealthy individuals. The company has thus developed a very accurate health DNA test that screens for a wide spectrum of genetic diseases and conditions.
Futura Genetics currently offers only one all-encompassing health DNA test. The price is 339EUR for European customers and 413EUR for users from the US and Canada. The test checks your genetic predisposition for 28 different genetic maladies. Some of the screened diseases include lung cancer, Alzheimer’s, migraine, melanoma, lupus, obesity, multiple sclerosis, alopecia, prostate and breast cancer, type 1 and 2 diabetes, and others. The test uses saliva to extract your DNA sample, so the entire sample collection procedure should take between 2 and 5 minutes.
The company also takes the privacy of its users very seriously. Your personal information will be stored within the EEA and processed by the company staff. SSL technology is
also incorporated in order to protect user data from potential hacking attacks. The Futura Genetics testing kit is completely anonymous; it’s identified via the unique barcode rather than your personal information. Finally, the company will never share your data with anyone or provide results over the phone or email.